Description
Florfenicol is a synthetic broad-spectrum antibiotic that is effective against most gram-positive and gram-negative bacteria isolated from domestic animals. florfenicol, a fluorinated derivative of chloramphenicol, acts by inhibiting protein synthesis at the ribosomal level and is bacteriostatic. florfenicol does not carry the risk of inducing human aplastic anaemia that is associated with the use of chloramphenicol, and also has activity against some chloramphenicol-resistant strains of bacteria.
Indications
Introflor-100 oral is indicated for preventive and therapeutic treatment of gastrointestinal and respiratory tract infections, caused by florfenicol sensitive micro-organisms such as actinobaccillus spp. pasteurella spp. salmonella spp. and streptococcus spp. in swine and poultry. the presence of the disease in the herd should be established before preventive treatment. medication should be initiated promptly when respiratory disease is diagnosed.
Dosage
For oral administration. the appropriate final dosage should be based on the daily water consumption.
Swine : 1 litre per 500 litre drinking water (200 ppm; 20 mg/kg body weight) for 5 days.
Poultry : 300 ml per 100 litre drinking water (300 ppm; 30 mg/kg body weight) for 3 days.
Contraindications
Not to be used in boars intended for breeding purposes, or in animals producing eggs or milk for human consumption.
Do not administer in cases of previous hypersensitivity to florfenicol.
The use of introflor-100 oral during pregnancy and lactation is not recommended.
The product should not be used or stored in galvanized metal watering systems or containers.
Side Effects
A decrease in food and water consumption and transient softening of the faeces or diarrhoea may occur during the treatment period. the treated animals recover quickly and completely upon termination of treatment.
In swine, commonly observed adverse effects are diarrhoea, peri-anal and rectal erythema/ oedema and prolapse of the rectum. these effects are transient.
Withdrawal period
For Meat:
Swine : 21 days.
Poultry : 7 days.
Storage
Store below 25ºC, in a cool and dry place, and protect from light.
For Veterinary Use Only.
Keep out of reach of children.
