Description
Doxycycline belongs to the group of tetracyclines and acts bacteriostatic against many Gram-positive and Gram-negative bacteria, like Bordetella, Campylobacter, E. coli, Haemophilus, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp. Doxycycline is also active against Chlamydia, Mycoplasma and Rickettsia spp. The action of doxycycline is based on inhibition of bacterial protein synthesis. Doxycycline has a great affinity to the lungs and is therefore especially useful for treatment of bacterial respiratory infections.
Indications
Gastrointestinal and respiratory infections caused by doxycycline sensitive micro-organisms, like Bordetella, Campylobacter, Chlamydia, E. coli, Haemophilus, Mycoplasma, Pasteurella, Rickettsia, Salmonella, Staphylococcus and Streptococcus spp. in calves, goats, poultry, sheep and swine.
Contra-indications
Hypersensitivity to tetracyclines.
Administration to animals of a seriously impaired hepatic function.
Concurrent administration with penicillins, cephalosporins, quinolones and cycloserine.
Administration to animals with an active microbial digestion.
Side effects
Discoloration of teeth in young animals may occur.
Hypersensitivity reactions may occur.
Dosage
For oral administration:
Calves, goats and sheep: 0.25-0.5g per 1L drinking water for 3 - 5 days.
Poultry and swine: 3g per 1L drinking water for 3 - 5 days.
Note: for pre-ruminant calves, lambs and kids only.
Withdrawal period
Meat:
Calves, goats and sheep: 14 days.
Swine: 8 days.
Poultry: 7 days.
Not for use in animals from which milk or eggs are produced for human consumption.
Storage
Store below 25ºC, in a cool and dry place, and protect from light.
For Veterinary Use Only.
Keep out of reach of children.
